Item Type | Name |
Concept
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Arrhythmias, Cardiac
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Concept
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Biotransformation
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Concept
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Amino Acid Sequence
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Concept
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Adenosine Triphosphate
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Concept
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Anions
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Concept
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Computer Simulation
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Concept
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Bacteriorhodopsins
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Concept
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Cadmium
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Concept
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Carbon Isotopes
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Concept
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Electricity
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Concept
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Electrons
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Concept
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Cell Membrane
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Concept
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Cross-Linking Reagents
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Concept
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Ciona intestinalis
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Concept
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Copper
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Concept
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Crystallography
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Concept
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Cysteine
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Concept
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Darkness
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Concept
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Hydrogen
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Concept
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Cytoplasm
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Concept
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Detergents
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Concept
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Diffusion
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Concept
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Drosophila
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Concept
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Edetic Acid
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Concept
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Electrophysiology
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Concept
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Energy Transfer
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Concept
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Fertilization
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Concept
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Drosophila melanogaster
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Concept
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Electric Conductivity
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Concept
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Spindle Apparatus
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Concept
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Ions
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Concept
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Halobacterium
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Concept
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Electron Spin Resonance Spectroscopy
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Concept
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Leishmania mexicana
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Concept
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Liposomes
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Concept
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Escherichia coli
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Concept
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Light
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Concept
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Maleimides
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Concept
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Magnesium
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Concept
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Leukocytes
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Concept
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Nitrates
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Concept
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Molecular Sequence Data
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Concept
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Mycobacterium tuberculosis
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Concept
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Micelles
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Concept
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Hot Temperature
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Concept
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Neutrophils
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Concept
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Oxygen Isotopes
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Concept
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Muscle Proteins
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Concept
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Oxygen
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Concept
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Potassium
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Concept
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Rubidium
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Concept
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Semen
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Concept
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Potassium Channels
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Concept
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Sodium
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Concept
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Hydrogen Bonding
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Concept
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Receptors, N-Methyl-D-Aspartate
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Concept
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Software
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Concept
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Caenorhabditis elegans
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Concept
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Sequence Homology, Amino Acid
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Concept
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Drug Design
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Concept
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Hair Cells, Auditory, Outer
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Concept
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Water
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Concept
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HIV Protease
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Concept
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Ion Channel Gating
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Concept
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Methanobacterium
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Concept
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Respiratory Burst
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Concept
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Microtubules
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Concept
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Nickel
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Concept
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Proton Pumps
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Concept
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Crystallography, X-Ray
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Concept
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Patch-Clamp Techniques
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Concept
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DNA, Complementary
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Concept
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Halobacterium salinarum
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Concept
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Kv1.3 Potassium Channel
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Concept
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Tetraethylammonium
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Concept
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Acrosome Reaction
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Concept
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Potassium Channel Blockers
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Concept
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Gap Junctions
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Concept
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Shaker Superfamily of Potassium Channels
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Concept
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Ether-A-Go-Go Potassium Channels
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Concept
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Amino Acid Motifs
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Concept
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Potassium Channels, Inwardly Rectifying
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Concept
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Phosphoric Monoester Hydrolases
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Concept
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Thiocyanates
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Concept
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HEK293 Cells
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Concept
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Static Electricity
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Concept
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Streptomyces lividans
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Concept
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Streptomyces
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Concept
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Tetraethylammonium Compounds
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Concept
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Open Reading Frames
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Concept
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Baculoviridae
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Concept
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ATP-Binding Cassette Transporters
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Concept
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Arabidopsis
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Concept
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Dimerization
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Concept
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Halorhodopsins
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Concept
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Cation Transport Proteins
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Concept
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Structural Homology, Protein
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Concept
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Kv1.2 Potassium Channel
|
Concept
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Escherichia coli Proteins
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Concept
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Aeropyrum
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Concept
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Axons
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Concept
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Carbon
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Concept
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Cochlea
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Concept
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Disease Models, Animal
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Concept
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Fluorescent Dyes
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Concept
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Haemophilus influenzae
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Concept
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Membrane Potentials
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Concept
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Protons
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Concept
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Sperm Capacitation
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Concept
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T-Lymphocytes
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Concept
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Cytokines
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Concept
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Methanococcus
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Concept
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DNA Primers
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Concept
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Computational Biology
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Concept
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Potassium Channels, Voltage-Gated
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Concept
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Potassium Channels, Calcium-Activated
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Concept
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Large-Conductance Calcium-Activated Potassium Channels
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Concept
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Molecular Dynamics Simulation
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Concept
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Coordination Complexes
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Academic Article
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy.
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Academic Article
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Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy.
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Academic Article
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Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability.
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Academic Article
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Shedding light on voltage-dependent gating.
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Academic Article
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pH-dependent gating in the Streptomyces lividans K+ channel.
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Academic Article
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Gating currents in Shaker K+ channels. Implications for activation and inactivation models.
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Academic Article
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Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
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Academic Article
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Structure of the KcsA channel intracellular gate in the open state.
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Academic Article
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Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis.
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Academic Article
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Structural rearrangements underlying K+-channel activation gating.
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Academic Article
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Site-directed spin-labeling analysis of reconstituted Mscl in the closed state.
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Academic Article
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EPR approaches to ion channel structure and function.
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Academic Article
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Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating.
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Academic Article
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Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
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Academic Article
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New structural perspectives on K(+) channel gating.
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Academic Article
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Structural biology. Force and voltage sensors in one structure.
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Academic Article
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Structure and mechanism in prokaryotic mechanosensitive channels.
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Academic Article
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions.
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Academic Article
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Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations.
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Academic Article
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Molecular basis of gating charge immobilization in Shaker potassium channels.
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Academic Article
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Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces.
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Academic Article
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Gating prokaryotic mechanosensitive channels.
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Academic Article
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Voltage-dependent gating at the KcsA selectivity filter.
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Academic Article
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An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis.
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Academic Article
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Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions.
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Academic Article
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Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis.
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Academic Article
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How to gate an ion channel: lessons from MthK.
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Academic Article
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Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF.
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Academic Article
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Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions.
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Academic Article
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Distinct gate conformations of the ABC transporter BtuCD revealed by electron spin resonance spectroscopy and chemical cross-linking.
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Academic Article
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Structural biology: A channel with a twist.
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Academic Article
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A molecular mechanism for proton-dependent gating in KcsA.
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Academic Article
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Molecular determinants of gating at the potassium-channel selectivity filter.
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Academic Article
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Design and characterization of a constitutively open KcsA.
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Academic Article
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Structural basis for the coupling between activation and inactivation gates in K(+) channels.
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Academic Article
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Ion conduction through MscS as determined by electrophysiology and simulation.
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Academic Article
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On the structural basis of modal gating behavior in K(+) channels.
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Academic Article
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Up a hydrophobic creek with a short paddle.
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Academic Article
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Dynamics of "flap" structures in three HIV-1 protease/inhibitor complexes probed by total chemical synthesis and pulse-EPR spectroscopy.
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Academic Article
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A quantitative description of KcsA gating I: macroscopic currents.
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Academic Article
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A quantitative description of KcsA gating II: single-channel currents.
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Academic Article
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Mechanism of activation gating in the full-length KcsA K+ channel.
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Academic Article
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Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
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Academic Article
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A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
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Academic Article
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Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data.
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Academic Article
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A structural mechanism for MscS gating in lipid bilayers.
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Academic Article
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Crystal structure of full-length KcsA in its closed conformation.
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Academic Article
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The activated state of a sodium channel voltage sensor in a membrane environment.
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Academic Article
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An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
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Academic Article
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Removal of transducer HtrI allows electrogenic proton translocation by sensory rhodopsin I.
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Academic Article
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A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
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Academic Article
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Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.
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Academic Article
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Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
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Academic Article
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Mechanism of Cd2+ coordination during slow inactivation in potassium channels.
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Academic Article
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Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate.
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Academic Article
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Gating of Shaker K+ channels: I. Ionic and gating currents.
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Academic Article
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S4 mutations alter gating currents of Shaker K channels.
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Academic Article
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Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system.
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Academic Article
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Three-dimensional architecture of membrane-embedded MscS in the closed conformation.
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Academic Article
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Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation.
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Academic Article
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Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides.
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Academic Article
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The voltage sensor and the gate in ion channels.
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Academic Article
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Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer.
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Academic Article
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Explicit treatment of spin labels in modeling of distance constraints from dipolar EPR and DEER.
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Academic Article
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Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
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Academic Article
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Molecular driving forces determining potassium channel slow inactivation.
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Academic Article
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Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer.
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Academic Article
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Structural mechanism of C-type inactivation in K(+) channels.
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Academic Article
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Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer.
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Academic Article
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Protein conformational dynamics in the mechanism of HIV-1 protease catalysis.
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Academic Article
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Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS).
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Academic Article
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Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels.
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Academic Article
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Binding of the CYK-4 subunit of the centralspindlin complex induces a large scale conformational change in the kinesin subunit.
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Academic Article
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Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP.
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Academic Article
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xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures.
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Academic Article
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Recovery from slow inactivation in K+ channels is controlled by water molecules.
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Academic Article
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Importance of lipid-pore loop interface for potassium channel structure and function.
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Academic Article
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Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain.
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Academic Article
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Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
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Academic Article
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A repulsion mechanism explains magnesium permeation and selectivity in CorA.
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Academic Article
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Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating.
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Academic Article
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Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP.
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Academic Article
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Conformational dynamics at the inner gate of KcsA during activation.
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Academic Article
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Molecular mechanism of Mg2+-dependent gating in CorA.
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Academic Article
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Biomolecular DNP-Supported NMR Spectroscopy using Site-Directed Spin Labeling.
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Academic Article
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Resting state of the human proton channel dimer in a lipid bilayer.
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Academic Article
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Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.
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Academic Article
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Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
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Academic Article
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Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel.
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Academic Article
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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.
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Academic Article
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Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
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Academic Article
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From Nanodiscs to Isotropic Bicelles: A Procedure for Solution Nuclear Magnetic Resonance Studies of Detergent-Sensitive Integral Membrane Proteins.
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Academic Article
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Toward a structural blueprint for bilayer-mediated channel mechanosensitivity.
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Academic Article
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Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.
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Academic Article
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Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.
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Academic Article
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The gating cycle of a K+ channel at atomic resolution.
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Academic Article
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Towards a Structural View of Drug Binding to hERG K+ Channels.
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Academic Article
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Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.
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Academic Article
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Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.
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Academic Article
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Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.
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Academic Article
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Structural Dynamics of the MscL C-terminal Domain.
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Academic Article
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De novo GRIN variants in NMDA receptor M2 channel pore-forming loop are associated with neurological diseases.
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Academic Article
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Real time dynamics of Gating-Related conformational changes in CorA.
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Academic Article
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Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
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Academic Article
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Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
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Academic Article
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Mechanism of C-type inactivation in the hERG potassium channel.
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Academic Article
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Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils.
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Academic Article
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Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel.
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Academic Article
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The conformational cycle of prestin underlies outer-hair cell electromotility.
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Academic Article
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Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative.
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Academic Article
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Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
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Academic Article
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Mechanism of voltage gating in the voltage-sensing phosphatase Ci-VSP.
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Academic Article
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State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
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Concept
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ERG1 Potassium Channel
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Concept
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Protein Domains
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Concept
|
Cell Surface Display Techniques
|
Concept
|
Methanocaldococcus
|
Grant
|
MOLECULAR ARCHITECTURE OF POTASSIUM CHANNELS
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Academic Article
|
Folding of Prestin's Anion-Binding Site and the Mechanism of Outer Hair Cell Electromotility.
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Academic Article
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Conformation-specific synthetic antibodies discriminate multiple functional states of the ion channel CorA.
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Academic Article
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Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
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Academic Article
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Anionic omega currents from single countercharge mutants in the voltage-sensing domain of Ci-VSP.
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Academic Article
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Folding of prestin's anion-binding site and the mechanism of outer hair cell electromotility.
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